Exciting postdoc Opportunity: Tracking memories in single NEuron patterns in the Human Brain

Recruiting postdoc for 5-year ERC-funded project on human memory reconstruction

Applications are invited for a postdoctoral research fellow to join the Adaptive Memory Lab in summer 2017. The position is funded by a 5-year European Research Council (ERC) grant awarded to Dr Maria Wimber. The project's aim is to map the time course of remembering within distributed, memory-triggered patterns of human brain activity. It uses a very multimodal brain imaging approach, including intracranial EEG, EEG-fMRI, MEG, and high-field fMRI. The postdoc will mainly be involved in the iEEG aspects of the project - LFP and single-nit recordings from the human hippocampus and temporal lobes -, which are conducted in close collaboration with the Queen Elisabeth Hospital Birmingham and other members of the Birmingham Memory Group. This is an exciting opportunity for researchers with a strong background in (human or animal) electrophysiology, and a general interest in memory.

More details about the post and an application link can be found here.

For informal enquiries, feel free to contact Maria Wimber directly by email.


PhD Students wanted:

Neurophysiological markers of memory acquisition and persistence

Neural oscillations coordinate and synchronise activity in multiple brain regions. During memory formation in humans, there is a complex pattern of synchronised activity in the hippocampus paralleled by desynchronization in the cortex. This project will investigate how these two phenomena interact during memory formation and retrieval.

The project will test the hypothesis that the combination of cortical desynchronization and hippocampal synchrony enables synaptic plasticity to occur. To achieve this, the activity of single units in the hippocampus and cortex will be recorded in awake rats while they encode a new memory.

The project will then progress to studying the presence of similar phenomena during memory reactivation and reconsolidation. Students will receive state-of-the-art training in rodent behavioural testing, electrode implantation and electrophysiological recording, and analysis of oscillatory activity.

We will first establish a learning paradigm that provides an analogue of those used in human studies. Then, the core neurophysiological recordings and analyses will be conducted. In parallel, behavioural studies of memory consolidation and reconsolidation will be carried out in the novel paradigm.

The successful candidate will be based in Birmingham and work in the labs of Dr. Jonathan Lee, and Dr Simon Hanslmayr, in collaboration with Dr Carl Stevenson from the University of Nottingham.